Compounds > 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol

Page last updated: 2024-08-24

4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol and raloxifene

4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol has been researched along with raloxifene in 10 studies

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	2 (20.00)	18.2507
2000's	5 (50.00)	29.6817
2010's	3 (30.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Adrian, MD; Bryant, HU; Cho, S; Cole, HW; Finley, DR; Glasebrook, AL; Godfrey, AG; Grese, TA; Jones, CD; Lugar, CW; Magee, DE; Martin, MJ; Matsumoto, K; Pennington, LD; Phillips, DL; Rowley, ER; Short, LL; Winter, MA	1
Adrian, MD; Bryant, HU; Cole, HW; Fuson, TR; Glasebrook, AL; Grese, TA; Magee, DE; Pennington, LD; Phillips, DL; Rowley, ER; Sato, M; Shetler, PK; Short, LL; Sluka, JP; Venugopalan, M; Yang, NN	1
Dodge, JA; Jones, SA; Lauwers, KS; Wallace, OB	1
Bischoff, SF; Buhl, T; Floersheim, P; Fournier, B; Halleux, C; Kallen, J; Keller, H; Renaud, J; Schlaeppi, JM; Stark, W	1
Bhagwat, SS; Brady, H; Doubleday, M; Gayo, L; Hickman, M; Jalluri, RK; Khammungkhune, S; Kois, A; McKie, JA; Mortensen, D; Richard, N; Sapienza, J; Shevlin, G; Stein, B; Sutherland, M	1
Clegg, NJ; Leitman, DC; Paruthiyil, S; Scanlan, TS	1
Armstrong, MD; Arteaga, CL; Brown, HA; Buck, JR; Cho, HP; Criswell, TL; Lindsley, CW; Scott, SA; Selvy, PE; Thomas, AL	1
Dettmann, S; Gust, R; Müller, CE; Schiedel, A; Szymanowitz, K; Wellner, A	1
Dadiboyena, S	1
Bryant, HU; Chalmers, MJ; Dodge, JA; Griffin, PR; Montrose-Rafizdeh, C; Novick, S; Sato, M; Wang, Y	1

Reviews

1 review(s) available for 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol and raloxifene

Article	Year
Recent advances in the synthesis of raloxifene: a selective estrogen receptor modulator. European journal of medicinal chemistry, 2012, Volume: 51 Topics: Cell Line, Tumor; Chemistry Techniques, Synthetic; Humans; Isotope Labeling; Organometallic Compounds; Raloxifene Hydrochloride; Receptors, Estrogen; Selective Estrogen Receptor Modulators	2012

Other Studies

9 other study(ies) available for 4-[1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol and raloxifene

Article	Year
Structure-activity relationships of selective estrogen receptor modulators: modifications to the 2-arylbenzothiophene core of raloxifene. Journal of medicinal chemistry, 1997, Jan-17, Volume: 40, Issue:2 Topics: Adenocarcinoma; Animals; Binding Sites; Bone and Bones; Breast Neoplasms; Cell Division; Cholesterol; Estrogen Antagonists; Female; Humans; Male; Organ Size; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Structure-Activity Relationship; Uterus	1997
Synthesis and pharmacology of conformationally restricted raloxifene analogues: highly potent selective estrogen receptor modulators. Journal of medicinal chemistry, 1998, Apr-09, Volume: 41, Issue:8 Topics: Animals; Bone Density; Cell Division; Cholesterol; Estrogen Antagonists; Female; Gene Expression Regulation; HeLa Cells; Humans; Models, Molecular; Molecular Conformation; Naphthoquinones; Organ Size; Ovariectomy; Piperidines; Raloxifene Hydrochloride; Rats; Rats, Sprague-Dawley; Receptors, Estrogen; Structure-Activity Relationship; Transforming Growth Factor beta; Tumor Cells, Cultured; Uterus	1998
Tetrahydroquinoline-based selective estrogen receptor modulators (SERMs). Bioorganic & medicinal chemistry letters, 2003, Jun-02, Volume: 13, Issue:11 Topics: Cell Division; Cell Line, Tumor; Humans; Hydroxyquinolines; Inhibitory Concentration 50; Ligands; Receptors, Estrogen; Selective Estrogen Receptor Modulators; Structure-Activity Relationship	2003
Estrogen receptor modulators: identification and structure-activity relationships of potent ERalpha-selective tetrahydroisoquinoline ligands. Journal of medicinal chemistry, 2003, Jul-03, Volume: 46, Issue:14 Topics: Administration, Oral; Animals; Binding Sites; Biological Availability; Cell Division; Crystallography, X-Ray; Estradiol; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogen Receptor Modulators; Female; HeLa Cells; Humans; Isoquinolines; Ligands; Models, Molecular; Radioligand Assay; Raloxifene Hydrochloride; Rats; Receptors, Estrogen; Stereoisomerism; Structure-Activity Relationship; Transcription, Genetic; Tumor Cells, Cultured	2003
Lead identification of a potent benzopyranone selective estrogen receptor modulator. Bioorganic & medicinal chemistry letters, 2004, Jul-05, Volume: 14, Issue:13 Topics: Animals; Binding Sites; Coumarins; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor Modulators; Female; Interleukin-6; Molecular Structure; Piperidines; Raloxifene Hydrochloride; Tamoxifen; Tumor Cells, Cultured	2004
Differential response of estrogen receptor subtypes to 1,3-diarylindene and 2,3-diarylindene ligands. Journal of medicinal chemistry, 2005, Sep-22, Volume: 48, Issue:19 Topics: Antineoplastic Agents; Binding, Competitive; Cell Line, Tumor; Cell Proliferation; Estradiol; Estrogen Antagonists; Estrogen Receptor alpha; Estrogen Receptor beta; Fluorescence Polarization; Fluorescent Dyes; Genes, Reporter; Humans; Indenes; Ligands; Response Elements; Structure-Activity Relationship	2005
Design of isoform-selective phospholipase D inhibitors that modulate cancer cell invasiveness. Nature chemical biology, 2009, Volume: 5, Issue:2 Topics: Breast Neoplasms; Drug Design; Enzyme Inhibitors; Humans; Isoenzymes; Neoplasm Invasiveness; Phospholipase D	2009
2-phenyl-1-[4-(2-piperidine-1-yl-ethoxy)benzyl]-1H-benzimidazoles as ligands for the estrogen receptor: synthesis and pharmacological evaluation. Bioorganic & medicinal chemistry, 2010, Jul-15, Volume: 18, Issue:14 Topics: Antineoplastic Agents; Benzimidazoles; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Estrogen Receptor beta; Female; Gene Expression Regulation, Neoplastic; Humans	2010
Hydrophobic Interactions Improve Selectivity to ERα for Ben-zothiophene SERMs. ACS medicinal chemistry letters, 2012, Mar-08, Volume: 3, Issue:3 Topics:	2012